The Future of Health: Genetic Testing
by Dr Luis Felipe Menezes Martins - Clinical Director at Kurotel
With the conclusion of the Human Genome Project, the numbers of genetic testing have grown considerably – providing us with information that is revolutionizing our understanding of who we are. The fast lane of discovery on the human genome allows an accurate diagnosis of a number of genetic diseases, as well as helping to identify the predisposition of a healthy person to develop certain types of diseases.
Thus results of those tests tell us about a person’s risk of developing a specific disorder and what kind of care is needed for prevention.
Genetic testing provides information about a person’s genes and chromosomes and thus a diagnosis for diseases like Down Syndrome and sickle cell anaemia. Predictive testing can identify gene mutations that increase a person's risk of developing disorders with a genetic basis, such as certain types of cancer. Pre-symptomatic testing can determine whether a person will develop a genetic disorder before any signs or symptoms appear.
It is important to understand that the tests only show a genetic predisposition, meaning that the situation might never occur. In some cases it is not a specific treatment, but an accurate diagnosis that can significantly improve the quality of life, prevent the appearance of symptoms and avoid unnecessary treatments.
Further, it can help in the process of deactivating bad genes, for example through a balanced diet, regular physical exercises and emotional balance.
Genetic testing can verify that the same diet can promote different metabolic and clinic effects to different people. There is a gene modulation, which regulates the feeling of satisfaction and the fat burn response during physical exercise, while others confer a predisposition to eating behaviors and provide information on how the organism processes fat, proteins and carbohydrates.
We humans are 99,9 per cent genetically identical, which means that only a tiny 0,1 per cent of our genome differ us from one another. All we know about food and eating behavior is scientifically correct, but not the same method is applicable for everyone.
Each person has a unique metabolism and that is where predictive genetic testing benefits take place.
The main goal of tests using nutritional genomics is to better understand eating behaviors, verify the ability of a person to metabolize micro and macronutrients, see the food profile and the most recommended type of protein, carbohydrates and fats, analyze lipolysis, predisposition to rebound effect, response to physical exercise and emotional/behavioral factors.
It is also possible to identify food intolerances to gluten and lactose as well as the ability to metabolize certain substances as caffeine, which in slow rate can increase excitement, which affects sleeping and increases the risk of acute myocardial infarction.
This exceptional tool uses your genome to customize a diet regimen and an exercise routine based on your DNA.
The predictive tests that assess the nutritional queries related to physical exercise are an additional tool allowing a genetic change to prevent or manage a disease. Obviously, it doesn’t replace the expert advice of nutritionists, fitness experts and physicians. However, predictive genetic testing provides information to reduce the risk of developing certain types of diseases and promote health in a more effective way.
Understanding the nutritional profile, specially the factors relying on genetics that are keeping you from achieving or maintaining a healthy weight, helps to direct the interventions most efficiently. The proportion of carbohydrates, fat and proteins should follow the genetic nutritional profile, as well as vitamin and minerals dosages. With this information at hand, we can achieve a better outcome to reduce calories, the rebound effect, emotional and behavioral management and improve physical exercise.
The data from genetic testing related to exercise allows to improve training and performance.
The data from genetic testing related to exercise, like the type of prevailing muscle fibre, oxidative stress, lipolysis and inflammatory levels allows to improve training and performance, as well to define the exercise program that is most likely to match your genes. It includes sports (detect talents), prevent injuries and overtraining, avoid performance loss, determine intensity, training time and breaks, adjust macronutrients intake before and after training and regulate lipolysis to achieve optimum results.
We at Kurotel – Longevity Medical Center and Spa, believe that predictive genetic testing is an exceptional tool to help identify a gene predisposition to develop specific disorders related to diet and exercise as well as chronic-degenerative diseases like heart and brain disease, diabetes type II, insulin resistance and Alzheimer.
The Kurotel encourages a balanced diet, regular physical exercise and management of emotions to take positive and preventative actions to boost health and vitality.
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